The Effects of Dietary Probiotic and Antibiotic Supplementations on Health Characteristics of Rainbow Trout

Abstract

The aim of this study was to assess the effect of dietary antibiotic (amoxycillin/clavulanic acid) and probiotic on the some immunological and serum biochemical health characteristics of rainbow trout (Oncorhynchus mykiss). Lysozyme activity, myeloperoxidase activity, total protein, albumin, globulin, triglyceride and cholesterol of rainbow trout was not affected by any of the dietary additives tested. The serum glucose in antibiotic group was significantly higher than the control group. However, the GOT level in antibiotic group was lower than the control group. In addition, compared with the control group, the LDH and ALP were deceased significantly in the antibiotic and probiotic treatments. This study is a single experimental model, and further investigations on the use of different concentrations of probiotic in different fish species and different fish pathogens are encouraged in terms of the evaluation of various blood parameters, since it is likely that the responses of fish seem to be subject to change in relation to different doses or time.