Antioxidant, Antibacterial Activities and Synergistic Effect with Antibiotics of Fruits and Stems Extracts from Styphnolobium japonicum (L.) Schott
DOI:
https://doi.org/10.24925/turjaf.v11i2.383-389.5362Anahtar Kelimeler:
Antimicrobial activity- Antioxidants- Flavonoids- Polyphenols- Sophora japonicaÖzet
The objective of this study was to evaluate the antioxidant and antibacterial properties of Styphnolobium japonicum (L.) Schott extracts. Results showed that the total phenols and flavonoids contents of the extracts ranged from 24.57 to 316.11 mg GAE/g and from 1.80 to 12.41μg QE/mg, respectively. Ethyl acetate (EaES) and aqueous (AqES) extracts from seeds showed the highest DPPH scavenging capacity (IC50= 5.51 and 23.43 μg/mL). EaES from seeds, stem bark and fruit pod were the most active in inhibiting β-carotene oxidation. While, aqueous extracts have the ability to chelate ferrous ions. Significant antibacterial activity was obtained against Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Salmonella typhimurium, Listeria monocytogenes, Bacillus cereus and Pseudomonas aeroginosa; and inhibition zones varied between 10 to 29.5 mm. MIC and MBC ranged from 0.7–11.25 mg/mL and 5.63–22.5 mg/mL, respectively. In addition, synergistic effects were obtained, where inhibition zones varied between 7 and 50 mm. These results support the use of this species in traditional medicine in many physiological disorders and could be used where antioxidant and antibacterial are warranted.
Referanslar
Adjadj M, Djarmouni M, Baghiani A. 2017. Xanthine oxidase inhibitory activity and antioxidant property of various Extracts from the medicinal plant Paronychia argentea L. Asian Journal of Biotechnology and Bioresource Technology, 2(3): 1-9.
Akgül H, Mohammed FS, Kına E, Uysal İ, Sevindik M, Doğan M. 2022. Total Antioxidant and Oxidant Status and DPPH Free radical activity of Euphorbia eriophora. Turkish Journal of Agriculture-Food Science and Technology, 10(2): 272-275.
Akinbobola AB, Dada EO. 2014. In-vitro evaluation of the synergistic antimicrobial activities of Zingiber officinale (Rosc) and Tridax procumbens (Linn) against selected pathogenic bacteria. Journal of Medicinal Plant and Herbal Therapy Research, 2: 16-22.
Aouachria S, Boumerfeg S, Benslama A, Benbacha F, Guemmez T, Khennouf S, Arrar L, Baghiani A. 2017. Acute, sub-acute toxicity and antioxidant activities (in vitro and in vivo) of Reichardia picroide crude extract. Journal of Ethnopharmacology, 208: 105-116.
Benites RSR, Formagio ASN, Argandoña EJS, Volobuff CRF, Trevizan LNF, Vieira MC, Silva MS. 2015. Contents of constituents and antioxidant activity of seed and pulp extracts of Annonacoriacea and Annonasylvatica. Brazilian Journal Biology, 75(5): 685-691.
Cai Y, Luo Q, Sun M, Corke H. 2004. Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer. Life Science, 74(17): 2157-2184.
Chokki M, Cudălbeanu M, Zongo C, Dah-Nouvlessounon D, Ghinea IO, Bianca F, Raclea R, Savadogo A, Baba-Moussa L, Avamescu SM, Dinica RM, Baba-Moussa F. 2020. Exploring Antioxidant and Enzymes (A-Amylase and B-Glucosidase) Inhibitory Activity of Morinda lucida and Momordica charantia Leaves from Benin. Foods, 9: 434.
Clinical and Laboratory Standards Istitute-CLSI. 2015. Performance Standards for antimicrobial disk susceptibility test. Twelve edition. Wayne, PA: Approved Standard, M02-A12.
Domínguez R, Pateiro M, Gagoua M, Barba FJ, Zhang W, Lorenzo JM. 2019. A Comprehensive Review on Lipid Oxidation in Meat and Meat Products. Antioxidants (Basel), 8(10): 429.
Ebelle Etam R, Simplice M., Cidjeu Pouaha CL, Voukeng Kenfack I, Tchientcheu R, Assam Assam J P, Monthe Poundeu FS, Tchinda Tiabou A, Etoa FX, Jules R, Kuiate JR, Ngono Ngane RA. 2018. Effect of fractioning on antibacterial activity of Enantia chlorantha oliver (Annonaceae) methanol extract and mode of action. Hindawi Evidence Based Complementary Alternative Medicine, 2018: 13.
Guemmaz T, Zerargui F, Boumerfeg S, Arrar L, Aouachria S, Khennouf S, Charef N, Baghiani A. 2018. Anti-hemolytic, anti-lipid peroxidation, antioxidant properties and acute toxicity of Xanthium strumarium leaves extracts. Annual Research & Review in Biology, 24(3): 1-12.
Gόrniak I, Bartoszewski R, Krόliczewski J. 2019. Comprehensive review of antimicrobial activities of plant flavonoids. Phytochemistry Reviews, 18: 241-272.
Ha DT, Trung TN, Phuong TT, Yim N, Chen QC, Bae K. 2010. The selected flavonol glycoside derived from Sophorae flos improves glucose uptake and inhibits adipocyte differentiation via activation AMPK in 3T3-L1 cells. Bioorganic Medical Chemistry Letter, 20: 6076-6081.
Han BH, Takeatsu K, Paul PH, But Guo JX and Sung CK. 1996. International collation of Traditional and folk medicine: Northeast Asia-Part I, World Scientific Publishing Co., Singapore, 68-69.
Iram H, Rasoo N, Riaz M, Zubair M, Rashid U, Bukhari IH, Tareen RB, Saiful Islam M. 2013. Antioxidant, antimicrobial, cytotoxicity and HPLC studies of Sophora mollis. Asian Journal of Chemistry, 25(18): 10519-10525.
Katerere DR, Eloff JN. 2008. Anti-Bacterial and Anti-Oxidant Activity of Hypoxi shemerocallidea (Hypoxidaceae): Can Leaves Be Substituted for Corms as a Conservation Strategy? South African Journal of Botany, 74: 613-616.
Khameneh B, Iranshahy M, Soheili V, FazlyBazzaz BS. 2019. Review on plant antimicrobials: a mechanistic viewpoint. Antimicrobial Resistance and Infection Control, 8: 118.
Kına E, Uysal İ, Mohammed FS, Doğan M, Sevindik M. 2021. In-vitro antioxidant and oxidant properties of Centaurea rigida. Turkish Journal of Agriculture-Food Science and Technology, 9(10): 1905-1907.
Kim HJ, Kim MK, Shim JG, Yeom SH, Kwon SH, Lee M.W. 2004. Anti-oxidative phenolic compounds from Sophorae Fructus. Natural Product Science, 10: 330-334.
Kim JM, Yun-Choi H.S. 2008. Anti-platelet Effects of Flavonoids and Flavonoid-glycosides from Sophora japonica. Archives of Pharmacal Research, 31(7): 886-890.
Krupodorova T, Barshteyn V, Sevindik M. 2022. Antioxidant and antimicrobial potentials of mycelial extracts of Hohenbuehelia myxotricha grown in different liquid culture media. BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology, 103(1):19-28.
Lee HK, Kim HS, Kim YJ, Kim JS, Park YS, Kang JS, Yuk DY, Hong JT, Kim Y, Han SB. 2013. Sophoricoside isolated from Sophora japonica ameliorates contact dermatitis by inhibiting NF-κB signaling in B cells. International Immunopharmacology, 15: 467-473.
Liguori I, Russo G, Curcio F, Bulli G, Aran L, Della-Morte D, Gargiulo G, Testa G, Cacciatore F, Bonaduce D, Abete P. 2018. Oxidative stress, aging, and diseases. Clinical Interventions in Aging, 13: 757-772.
Ma LH, He JP, Qin WD, Wang P, Liu HY. 2007. Study on anti-oxidative activities of pogada tree flower (Robinia Pseudocacia) extracts. Food Science, 28(9): 75-77.
Makarewicz M, Drożdż I, Tarko T and Duda-Chodak A. 2021. The interactions between polyphenols and microorganisms especially gut microbiota. Antioxidants, 10(2): 188.
Mogana R, Adhikari A, Tzar MN, Ramliza R, Wiart C. 2020. Antibacterial activities of the extracts, fractions and isolated compounds from Canarium patentinervium Miq. Against bacterial clinical isolates. BMC Complementary alternative Medicine, 20(1): 55.
Mohammed FS, Kına E, Uysal İ, Mencik K, Dogan M, Pehlivan M, Sevindik M. 2022. Antioxidant and Antimicrobial Activities of Ethanol Extract of Lepidium spinosum. Turkish Journal of Agriculture-Food Science and Technology, 10(6): 1116-1119.
Moldogazieva NT, Mokhosoev IM, Feldman NB, Lutsenko SK. 2018. ROS and RNS signalling: adaptive redox switches through oxidative/nitrosative protein modifications. Free Radical Research, 52: 507-543.
Park SJ, Shin EH, Hahm TS. 2009. Biological Activities in the Extract of Flos Sophora japonica L. Journal of the Korean Society of Food Science and Nutrition, 38(1): 1-13.
Pehlivan M, Mohammed FS, Şabik AE, Kına E, Dogan M, Yumrutaş Ö, Sevindik M. 2021. Some Biological activities of ethanol extract of Marrubium globosum. Turkish Journal of Agriculture-Food Science and Technology, 9(6): 1129-1132.
Ran XD, ZhonghuY. 1998. Harbin Publishing Press, 1982-1984.
Russo D. 2018. Flavonoids and the structure-antioxidant activity relationship. Journal of Pharmacognosy and Natural Product, 4(1): e109.
Saffidine K, Sahli F, Zeroug MH. 2015. Antioxidant and antimicrobial activities of Plantago major. International Journal of Pharmacy and Pharmaceutical sciences, 7(5): 58-64.
Salehi B, Azzini E, Zucca P, Varoni EM, Anil Kumar NV, Dini L, Panzarini E, Rajkovic J, TsouhFokou PV, Peluso I, Mishra AP, Nigam M, El Rayess Y, El Beyrouthy M, Setzer WN, Polito L, Iriti M, Sureda A, Quetglas-Llabrés MM, Martorell M, Martins N, Mehdi Sharifi-Rad M, Estevinho LM, Sharifi-Rad J. 2020. Plant-derived bioactives and oxidative stress-related disorders: a key trend towards healthy aging and longevity promotion. Applied Science, 10: 947.
Saratale RG, Benelli G, Kumar G, Kim DS, Saratale GD. 2018. Bio-fabrication of silver nanoparticles using the leaf extract of an ancient herbal medicine, dandelion (Taraxacumocinale), evaluation of their antioxidant, anticancer potential and antimicrobial activity against phytopathogens. Environmental Science of Pollution and Research, 25: 10392-10406.
Sevindik M, Akgul H, Pehlivan M, Selamoglu Z. 2017. Determination of therapeutic potential of Mentha longifolia ssp. longifolia. Fresen Environ Bull, 26(7): 4757-4763.
Trabsa H, Krach I, Boussoualim N, Ouhida S, Arrar L, Baghiani A. 2020. Evaluation of anti-inflammatory and antioxidant activities of Sedum sediforme extracts. Tropical Journal of Pharmaceutical Research, 19 (10): 2109-2114.
Unal O, Eraslan EC, Uysal I, Mohammed FS, Sevindik M, Akgul H. 2022. Biological activities and phenolic contents of Rumex scutatus collected from Turkey. Fresenius Environmental Bulletin, 31(7): 7341-7346.
Uysal İ, Mohammed FS, Şabik AE, Kına E, Sevindik M. 2021. Antioxidant and Oxidant status of medicinal plant Echium italicum collected from different regions. Turkish Journal of Agriculture-Food Science and Technology, 9(10): 1902-1904.
Wang K, Lin RF, Yen-Hua Huang Y, Chang H, Huang C, Lee M. 2006. Cosmetic applications of selected traditional Chinese herbal medicines. Journal of Ethnopharmacology, 106: 353-359.
Zerargui F, Boumerfeg S, Charef N, Baghiani A, Djarmouni M, Khennouf S, Arrar L, Abu Zarga MH, Mubarak MM. 2015. Antioxidant potentials and xanthine oxidase inhibitory effect of two furanocoumarins isolated from Tamus communis L. Journal of Medicinal Chemistry, 11(5): 506-513.
Zhang L, Ravipati AS, Koyyalamudi SR, Jeong SC, Reddy N, Smith PT, Bartlett J, Shanmugam K, Münch G, Wu MJ. 2011. Antioxidant and anti-inflammatory activities of selected medicinal plants containing phenolic and flavonoid compounds. Journal of Agricultural and Food Chemistry, 59: 12361-12367.
İndir
Yayınlanmış
Nasıl Atıf Yapılır
Sayı
Bölüm
Lisans
Bu çalışma Creative Commons Attribution-NonCommercial 4.0 International License ile lisanslanmıştır.
